LD50 / Median Lethal Dose

Autoři: Ing. Marek Brabec, PhD.
Rok vydání: 2012
Typ publikace: Kapitola v monografii
Periodikum: Encyclopedia of Mathematics and Society
Bibliografická citace: BRABEC, Marek. LD50 / Median Lethal Dose. In: GREENWALD, S.J., THOMLEY, J.R., eds. Encyclopedia of Mathematics and Society. 1. Ipswich: Salem Press, 2012, S. 535-536. ISBN 978-1-58765-845-7.
ID: 376188

Abstrakt

The median lethal dose of a compound is determined through experiment and statistical estimation. We describe how the dose response curve upon which median lethal dose is modeled statistically and how are the parameters of such a model estimated and used for the LD50 construction.